Xenadrine 40 plus from Cytodyne:

Helps Boost Slower Metabolisms In Adults Over 40!

Born out of the latest anti-aging research, Xenadrine 40+ is the first diet supplement specially designed to help revitalize cellular metabolism* in adults over 40 for better weight loss results. Stimulant and ephedra free, it's safe, simple, and effective. Added to a healthy diet and moderate exercise program, its unique patented blend of ingredients helps revitalize cellular metabolism (metabolic efficiency) for better weight loss results.

Xenadrine 40+ contains a combination of active ingredients including UT 100 (Uncaria tomentosa), a mushroom complex, niacinamide, zinc and Norambrolide (Clary Sage Extract standardized for sclareolide). The Uncaria tomentosa is particularly significant since it was shown to help support DNA repair in a human volunteer trial.1 With the exception of Norambrolide, all of these ingredients in the potencies found in Xenadrine 40+ were tested in a clinical study2 with 14 adults over the age of 40.

The results were:

78.6% of the subjects lost weight without changing their diet or exercise patterns
35.7% of the subjects experienced less aches and pains
21.4% of the subjects experienced less fatigue
85.7% of the subjects had improvements in DNA repair

Although we could have stopped here, we decided to improve this already great formula with the addition of Norambrolide. This fermented sage compound has been shown in unpublished in-vitro research3 to increase levels of a cellular messenger called cAMP (cyclic adenosine monophosphate). The significance of this is that in some metabolic processes, cAMP is involved in activating cellular enzymes and other substances that help move fat out of the fat cells and promote the weight loss process; although no research has yet been done to demonstrate that Norambrolide will have this effect in humans. Xenadrine 40+ is naturally safe and is totally stimulant free. It contains no caffeine, ephedra, etc.

Foot Notes:
1.Sheng Y, et al. Phytomedicine 2001; 8(4):275-82.
2.Pero RW, , et al. Formulation and In vitro/In vivo Evaluation of Combining DNA Repair and Immune Enhancing Nutritional Supplements. Phytomedicine 2004 (accepted for publication).
3.Anonymous. Sclareolide Effect on cAMP in Two Cell Lines. Unpublished report by NovaScreen. 2003; 19 pp
*Revitalizes cellular metabolism (Pero RW, et al. Formulation and Clinical Evaluation of Combining DNA Repair and Immune Enhancing Nutritional Supplements (unpublished). University of Lund, Department of Cell and Molecular Biology. 2002; 17 pages.)